Thursday, October 30, 2008

Actinobacillus (Haemophilus) pleuropneumoniae

- morphology resembles Pasteurella

- hemorrhagic necrotizing pneumonia, fibrinous pleuritis in pigs
- high morbidity; lethality depends on environmental factors

- no healthy carriers
- survivors end up with chronic pneumonia
- transmission: aerosol

VIRULENCE FACTORS OTHER THAN LPS AND CAPSULE
- cytotoxins
- porcine transferin binding protein (lends host specificity)

therapy: penicillin

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