Thursday, October 30, 2008

Bordetella bronchiseptica

- can affect pigs, rabbits, guinea pigs, other rodents
- many afflictions (see notes) but notably rhinitis atrophicans: acute rhinitis progressing to deformations of the turbinate bones, nasal septum and upper jaw

VIRULENCE FACTORS OTHER THAN LPS (toxin), FIMBRIAE (colonizing factor)
- other colonizing factors: filamentous hemagglutinin, pertactin
- other toxins: adenylate cyclase (hemolysin), type 3 secretion system, dermonecrotic (heat-labile) toxin, tracheal cytotoxin, transferrin/lactoferrin binding proteins, siderophore

therapy: susceptibility testing

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