Subepidermal vesicular and pustular dermatitis

Possible causes:
- autoimmune disorders

• unlike pemphigus vulgaris, bullous pemphigoid involves hemidesmosomes. Autoantibody against pemphigoid antigen, an antigen in the basement membrane, is produced. No acantholytic cells present.

• epidermolysis bullosa is a group of mechanobullous disorders that affect structural integrity of the epidermal basement membrane zone. Most disorders that fall under this category are hereditary.