Thursday, October 23, 2008

Derm: concluding odds and ends

- perifolliculitis is inflammation around the hair follicle

- folliculitis is inflammation within the lumen

- furunculosis is follicle rupture

- ringworm is a type of fungus that uses keratin in hair and epidermis (decays it)

- demodex mites are part of normal canine facial flora. They proliferate when the immune system is suppressed.

- vasculitis must have 2 components


  • inflammatory cell infiltrate (in or around vessel wall)

  • vascular injury

- panniculitis results in damage to adiopocytes. Fatty acids are potent inflammatory mediators.

- hyperadrenocoricism occurs due to increased glucocorticoids, either endogenous or exogenous


  • hallmark lesion is calcinosis cutis: mineralization of dermal collagen

dermal fibrosis: involves loss of all adnexal units



  • fibroplasia is the proliferation of granulation tissue

  • fibrosis is the end stage of fibroplasia; involves increased collagen deposition with altered arrangement.

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